RNA Folding on Parallel Computers: The Minimum Free Energy Structures of Complete HIV Genomes
Secondary structure prediction is a standard tool in the analysis of RNA sequences. The prediction of RNA secondary structures is inherently non-local. This makes the analysis of long sequences (more than 4000 nucleotides) infeasible on present-day workstations. An implementation of the secondary structure prediction algorithm for hypercube-type parallel computers allows to compute efficientloy the structure of complete RNA virus genomes such as HIV-1 and other lentiviruses.
Year of publication: |
1995-10
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Authors: | Hofacker, Ivo L. ; Huynen, Martijn A. ; Stadler, Peter F. ; Stolorz, Paul E. |
Institutions: | Santa Fe Institute |
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