Cerda, Jose Francisco; Flanders, Kayla G.; Pessagno, … - 2021
Under physiological conditions, hemoglobin (Hb) and myoglobin (Mb) are subject to autoxidation, leading to the formation of ferric heme proteins with weakened globular structures and resulting in the loss of the heme cofactor. To gain further insights into the role of the heme pocket in the...