Orofino, Javier; Soto, Javier; Casado, Miguel A.; … - In: Applied Health Economics and Health Policy 8 (2010) 5, pp. 301-315
Background: Orphan drugs are indicated for the treatment of rare diseases which, in the EU, are defined as those with a … programmes into rare diseases, with the aim of developing new, safe and effective orphan drugs. Objectives: To describe the … status of orphan drugs in five countries in the EU (France, Germany, the UK, Italy and Spain), estimate the mean annual cost …