Ji-Hyung, Shin; Claire, Infante-Rivard; Jinko, Graham; … - In: Statistical Applications in Genetics and Molecular Biology 11 (2012) 2, pp. 1-23
In the case-parent trio design, unrelated children affected with a disease are genotyped along with their parents. Information may also be collected on environmental factors in the children. The design permits estimation and testing of genetic effects and gene-by-environment interaction....