Costa, Adriana Santos; Borges de Melo, Eduardo - In: International Journal of Quantitative … 1 (2016) 2, pp. 85-100
Thymidine phosphorylase (TP) is a multifunctional protein frequently overexpressed in many types of cancer. Considering the interest in new anticancer compounds, a QSAR study was carried out to investigate a set of uracil derivatives described as TP inhibitors. The only molecular descriptors...