Alfo' Marco; Alessio, Farcomeni; Luca, Tardella - In: Statistical Applications in Genetics and Molecular Biology 10 (2011) 1, pp. 1-19
We propose a robust model for discovering differentially expressed genes which directly incorporates biological significance, i.e., effect dimension. Using the so-called c-fold rule, we transform the expressions into a nominal observed random variable with three categories: below a fixed lower...