A, Hothorn Ludwig; Martin, Sill; Frank, Schaarschmidt - In: The International Journal of Biostatistics 6 (2010) 1, pp. 1-19
The analysis of dose-response relationships is a common problem in pre-clinical studies. For example, proportions such as mortality rates and histopathological findings are of particular interest in repeated toxicity studies. Commonly applied designs consist of an untreated control group and...