Slaughter, Richard L.; Cappelletty, Diane M. - In: PharmacoEconomics 14 (1998) 4, pp. 385-394
Therapeutic drug monitoring (TDM) of aminoglycoside antibacterials with the goal of minimising toxicity and maximising effectiveness has become routine. Successful management of serious infections requires the ability to achieve therapeutic peak concentrations, while maintaining low trough...