Majoros, William H.; Salzberg, Steven L. - 2004
state-of-the-art ab initio gene finding, as evidenced by the recentproliferation of GHMM implementations. While prevailing … implementing a global discriminative trainingprocedure for our GHMM-based gene finder. Our results show that significant … improvement inprediction accuracy can be achieved by this method.Conclusions: We conclude that training of GHMM-based gene finders …