Murat, Sariyar; Martin, Schumacher; Harald, Binder - In: Statistical Applications in Genetics and Molecular Biology 13 (2014) 3, pp. 15-15
Risk prediction models can link high-dimensional molecular measurements, such as DNA methylation, to clinical endpoints. For biological interpretation, often a sparse fit is desirable. Different molecular aggregation levels, such as considering DNA methylation at the CpG, gene, or chromosome...