A, Moyé Lemuel; Dejian, Lai; Kaiyan, Jing; Sarah, … - In: The International Journal of Biostatistics 7 (2011) 1, pp. 1-29
The assumptions that anchor large clinical trials are rooted in smaller, Phase II studies. In addition to specifying the target population, intervention delivery, and patient follow-up duration, physician-scientists who design these Phase II studies must select the appropriate response variables...