Juvenile hyaline fibromatosis (JHF) is considered a non frequent genetic, autosomic recessive; characterized by connective tissue disorder characterized by multiple subcutaneous nodules, gingival hypertrophy, osteolytic lesions, and joint deformities (contractures). As one of the main clinical...

The autosomic alteration due to a ring formation is a rare aberration of either chromosome 13 and 18 which is in relation with phenotipic malformations, neurologic problems and genital abnormalities. Two clinical polymalformed cases with skull treboliform dismorfies with early seizures and...

The majority of de novo structural chromosome aberrations in fetuses and newborns are considered being of cells of mammals for DNA damage during gametogenesis. 4617 chromosomal studies performed during 19 years (from 1992 to 2011), at Hospital Para El Niño Poblano in México, a total of 1596...

Chromosome trisomies are considered alterations in the chromosome number or structure. A trisomy is therefore a type of polysomy in which there are three chromosome copies, instead of the normal two. A trisomy is considered an aneuploidy or abnormal number of chromosomes. There are two different...

Chromosome aberrations are considered changes in the chromosome number or structure. The etiology factor is due to gametogenesis inborn error (meiosis) or during the zygote first cellular divisions. It might occurs during metaphase from the cellular cycle, where DNA loses are seen (clastogenic...