Abstract In randomized cancer screening trials where asymptomatic individuals are assigned to undergo a regimen of screening examinations or standard care, the primary objective typically is to estimate the effect of screening assignment on cancer-specific mortality by carrying out an...

Abstract Routinely collected administrative and clinical data are increasingly being utilized for comparing quality of care outcomes between hospitals. This problem can be considered in a causal inference framework, as such comparisons have to be adjusted for hospital-specific patient case-mix,...

Dynamic treatment regime is a decision rule in which the choice of the treatment of an individual at any given time can depend on the known past history of that individual, including baseline covariates, earlier treatments, and their measured responses. In this paper we argue that finding an...

Under the setting of a case-cohort design, covariate values are ascertained for a smaller subgroup of the original study cohort which typically is a representative sample from a population. Individuals with a specific event outcome are selected to the second stage study group as cases and an...

Under the setting of a case-cohort design, covariate values are ascertained for a smaller subgroup of the original study cohort which typically is a representative sample from a population. Individuals with a specific event outcome are selected to the second stage study group as cases and an...