Chang, Myron; Wu, Rongling; Wu, Samuel; Casella, George - In: Statistical Applications in Genetics and Molecular Biology 8 (2009) 1, pp. 16-16
We propose a method to detect the existence of quantitative trait loci (QTL) in a backcross population using a score test. Since the score test only uses the MLEs of parameters under the null hypothesis, it is computationally simpler than the likelihood ratio test (LRT). Moreover, because the...