Chen, Tianle; Wang, Yuanjia; Chen, Huaihou; Marder, Karen; … - In: Journal of the American Statistical Association 109 (2014) 507, pp. 1174-1187
We develop methods to accurately predict whether presymptomatic individuals are at risk of a disease based on their various marker profiles, which offers an opportunity for early intervention well before definitive clinical diagnosis. For many diseases, existing clinical literature may suggest...