Jann, Michael W.; Cohen, Lawrence J. - In: Disease Management and Health Outcomes 3 (1998) 3, pp. 115-129
Administration (FDA) of clozapine in 1989, no new antipsychotics had been introduced in the US for at least 10 years. Clozapine was … associated with schizophrenia were also shown to improve with clozapine. However, because of the problem of agranulocytosis and … the need for intensive blood count monitoring with clozapine, its usage became restricted. The cost of using clozapine was …