We address how to configure the supply chain for a new product for which the design has already been decided. The central question is to determine what suppliers, parts, processes, and transportation modes to select at each stage in the supply chain. There might be multiple options to supply a...

We consider the intertemporal social optimization problem of minimizing the present value of the costs incurred from both disease and treatment. Though the analysis is complicated by the analytical failure of concavity, we are able to substantially characterize both the long run equilibria and...

A two-level flexible manufacturing system is considered to be composed of several different production units Ui, 1≤i≤n, at the lower level and a section at the upper one. The section is required to produce a given target amount V by a given due date D subject to a chance constraint, i.e. the...

Optimization of structures with respect to performance, weight or cost is a well-known application of mathematical optimization theory. However optimization of structures with respect to weight or cost under probabilistic reliability constraints or optimization with respect to reliability under...

Optimization of structures with respect to performance, weight or cost is a well-known application of mathematical optimization theory. However optimization of structures with respect to weight or cost under probabilistic reliability constraints or optimization with respect to reliability under...