Search Results - subject:"Developmental biology"

Towards a Developmental Turn in Evolutionary Economic Geography?

Martin, Ron; Sunley, Peter - Disciplinegroep Economische Geografie, Faculteit … - 2014

Over the past couple of decades or so, there have been increasing moves within evolutionary theory to move beyond the neo-Darwinian principles of variety, selection and retention, and to incorporate development. This has led to a richer palette of concepts, mechanisms and models of evolution and...

Persistent link: https://www.econbiz.de/10010733944

Quantifying and correcting for the winner's curse in genetic association studies

Xiao, Rui; Boehnke, Michael - 2009

Genetic association studies are a powerful tool to detect genetic variants that predispose to human disease. Once an associated variant is identified, investigators are also interested in estimating the effect of the identified variant on disease risk. Estimates of the genetic effect based on...

Persistent link: https://www.econbiz.de/10009476594

Shrinkage estimation for robust and efficient screening of single-SNP association from case-control genome-wide association studies

Luo, Sheng; Mukherjee, Bhramar; Chen, Jinbo; … - 2009

Population-based case-control design has become one of the most popular approaches for conducting genome-wide association scans for rare diseases like cancer. In this article, we propose a novel method for improving the power of the widely used single-single-nucleotide polymorphism (SNP)...

Persistent link: https://www.econbiz.de/10009476620

From the cradle to the labor market? The effect of birth weight on adult outcomes

Devereux, Paul J.; Black, Sandra E.; Salvanes, Kjell G. - School of Economics, University College Dublin - 2007

Lower birth weight babies have worse outcomes, both short-run in terms of one-year mortality rates and longer run in terms of educational attainment and earnings. However, recent research has called into question whether birth weight itself is important or whether it simply reflects other...

Persistent link: https://www.econbiz.de/10011269200

From the cradle to the labor market? The effect of birth weight on adult outcomes

Devereux, Paul J.; Black, Sandra E.; Salvanes, Kjell G. - School of Economics, University College Dublin - 2007

Persistent link: https://www.econbiz.de/10011269376

Core journal literatures and persistent research themes in an emerging interdisciplinary field: Exploring the literature of evolutionary developmental biology

McCain, Katherine W. - In: Journal of Informetrics 4 (2010) 2, pp. 157-165

data from Journal Citation Reports, 2005–2007. Evo-Devo cites into Developmental Biology in all three years and exchanges …This paper reports two interrelated citation-based studies of the intellectual structure of Evolutionary Developmental … Biology (Evo-Devo). The core journals of Evo-Devo (Evolution & Development, Development, Genes & Evolution, and Journal of …

Persistent link: https://www.econbiz.de/10010795211

A cell-centered approach to developmental biology

Merks, Roeland M.H.; Glazier, James A. - In: Physica A: Statistical Mechanics and its Applications 352 (2005) 1, pp. 113-130

regulation and physical, generic mechanisms at multiple scales. As more physicists move into developmental biology, we need to be …

Persistent link: https://www.econbiz.de/10011059718

Individual and population sex allocation patterns

Frank, Steven A. - 1987

A variety of sex allocation models is considered in which (i) the reproductive returns on investment in males differ from the returns on investment in females, (ii) the amounts of resources available for reproduction vary in the population, (iii) the costs of making male and female reproductive...

Persistent link: https://www.econbiz.de/10009476993

Evaluation of methods for the estimation of mutation rates in cultured mammalian cell populations

Li, I-Chian; Chu, Ernest H. Y. - 1987

A systematic comparison of 5 different statistical methods for the estimation of mutation rate ([mu]) in cultured Chinese hamster V79 cells is presented. Fluctuation tests were performed with several large batches of parallel cell cultures each allowed to grow for a different length of time in...

Persistent link: https://www.econbiz.de/10009477407

A deterministic approach for the estimation of mutation rates in cultured mammalian cells

Li, I-Chian; Ho Wu, Shu-Chen; Fu, Jiliang; Chu, Ernest H. Y. - 1985

Unequal growth rates between mutant and wild-type cells in a large population constitute a problem for the estimation of mutation rate. Over a period of cell growth, a selective advantage of one cell type over the other might lead to considerable error in the estimation of mutation rate if equal...

Persistent link: https://www.econbiz.de/10009477269