Dieser Bericht untersucht die Folgen der COVID-19-Pandemie auf das Leistungsgeschehen der Krankenhäuser in Deutschland. Er untersucht außerdem, ob die im Jahr 2021 geleisteten Ausgleichszahlungen die Erlösminderungen der Krankenhäuser aufgrund des Rückgangs der Leistungsmenge ausgleichen...

We investigate the short- and long-term effects of hospitalization on different types of health care expenditures (HCE). A dynamic DID model with variation in treatment timing is specied and estimated using register data of individuals aged 50-70 residing in Milan, Italy, and observed over the...

Compared to cancers detected early, distant stage cancers are associated with lower survival, diminished quality of life, and higher costs. Evidence suggests that greater access to comprehensive health insurance (i.e., Medicare) improved early detection. Yet, few studies have evaluated the...

Immune checkpoint inhibitors-based cancer immunotherapy is yielding great clinical benefit, but its efficacy is limited in gastric cancer (GC) by the lack of T-cell infiltration in the tumor microenvironment. Notably, activating the DNA-sensitive cyclic GMP-AMP synthase-stimulator of interferon...

Extracellular vesicles (EVs) are lipid membrane enclosed nano-sized vesicles that are secreted by all known organisms. These vesicles are increasingly recognized as important circulating biomarkers for the diagnosis and prognosis of different diseases including various types of cancer, owing to...

As a new type of fluorescent agents, carbon dots (CDs) have revealed great potential in biomedical imaging applications attributed to their unique optical properties and good biocompatibility. However, engineering a versatile CDs nanoplatform integrating multifunctional imaging and therapeutic...

Development of advanced drug nanocarriers that can improve cancer thermotherapeutic efficacy, reduce side effect and drug resistance is of particular interests. In this work, pure and crystalline boron nitride nanosheets (BNNSs) were synthesized by a NaCl-template reaction with the yield over 1...

This study represents a new way of looking at health, by investigating the effect of aggregate cancer incidence rates on labour productivity, using a macroeconomic methodology. The health of the labour force is a key determinant of labour productivity, with poor health comes both physical and...

Objectives: We conducted a multi‑stakeholder survey to determine key areas where a joint European health technology assessment (HTA) could provide "additional benefit" compared to the status quo of many parallel independent national and subnational assessments. Methods: Leveraging three...