Lewin, Alex; Bochkina, Natalia; Richardson, Sylvia - In: Statistical Applications in Genetics and Molecular Biology 6 (2007) 1, pp. 36-36
We present a Bayesian hierarchical model for detecting differentially expressed genes using a mixture prior on the parameters representing differential effects. We formulate an easily interpretable 3-component mixture to classify genes as over-expressed, under-expressed and non-differentially...