ÃÂngquist, Lars; Ola Hössjer - In: Statistical Applications in Genetics and Molecular Biology 3 (2007) 1, pp. 5-5
In this article we describe and discuss implementation of a weighted simulation procedure, importance sampling, in the context of nonparametric linkage analysis. The objective is to estimate genome-wide p-values, i.e. the probability that the maximal linkage score exceeds given thresholds under...