We consider nested multiple response models which are used extensively in the area of pharmacometrics. Given the conditional nature of such models, differences in predicted responses are a consequence of different assumptions about how the models interact. As such, sequential versus simultaneous...

The paper provides a survey of 18 years’ progress that my colleagues, students (both former and current) and I made in a prominent research area in Psychometrics—Computerized Adaptive Testing (CAT). We start with a historical review of the establishment of a large sample foundation for CAT....