Wong, Weng Kee; Melas, Viatcheslav B.; Dette, Holger - Institut für Wirtschafts- und Sozialstatistik, … - 2004
We construct efficient designs for the Michaelis-Menten enzyme kinetic model capable of checking model assumption. An extended model, called EMAX model is also considered for this purpose. This model is widely used in pharmacokinetics and reduces to the Michaelis- Menten model for a specific...