This study explores the worldwide spatial evolution of scientific knowledge production in biotechnology in the period 1986-2008. We employ new methodology that identifies new key topics in biotech on the basis of frequent use of title worlds in major biotech journals as an indication of new...

Since Paul David published his economic histories of path dependent innovation the subject has exerted fascination upon scholars of innovation, technological change and, latterly, regional scientists and economic geographers. This paper speaks to the third and fourth of these communities in the...

The article presents a regional innovation policy model, based on the idea of constructing regional advantage. This policy model brings together concepts like related variety, knowledge bases and policy platforms. Related variety attaches great importance to knowledge spillovers across...

This paper investigates the impact of scientific relatedness on knowledge dynamics in biotech at the city level during the period 1989-2008. We assess the extent to which the emergence of new research topics and the disappearance of existing topics in cities are dependent on their degree of...

This paper investigates the relationship between the creation of new firms and the properties of the local knowledge bases, like coherence, cognitive distance and variety. By combining the literature on the knowledge spillovers of entrepreneurship and that on the recombinant knowledge approach,...

This paper analyzes the emergence of new technology-based sectors at the regional level. We focus on the specific case of nanotechnology as representative of an industry based on a technology still in infancy whose evolution can be reliably traced on the basis of filed patent submissions. We...