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Treatment changes in randomized trials are common: for example, in a trial evaluating psychotherapy, individuals allocated to psychotherapy may attend only partially or not at all; or in a trial evaluating a drug treatment, individuals allocated to no drug treatment may nevertheless receive the...
Persistent link: https://www.econbiz.de/10010929916
Multiple imputation is increasingly regarded as the standard method to account for partially observed data, but most methods have been based on cross-sectional imputation algorithms. Recently, a new multiple-imputation method, the two fold fully conditional specification (FCS) method, was...
Persistent link: https://www.econbiz.de/10009320957
Any analysis with incomplete data makes untestable assumptions about the missing data, and analysts are therefore urged to conduct sensitivity analyses. Ideally, a model is constructed containing a nonidentifiable parameter d, where d = 0 corresponds to the assumption made in the standard...
Persistent link: https://www.econbiz.de/10009320968
This paper presents the methodology developed to collect, understand and merge viewpoints coming from different stakeholders in order to build a shared and formal representation of the studied system dealing with groundwater management in the low-lying atoll of Tarawa (Republic of Kiribati). The...
Persistent link: https://www.econbiz.de/10004983498
A new command metamiss performs meta-analysis when some or all studies have missing data. A variety of assumptions are available, including missing-at-random, missing=failure, worst and best cases, and incorporating a user-specified prior distribution for the degree of informative missingness....
Persistent link: https://www.econbiz.de/10005102765
Simulation studies are a powerful tool, but their analysis is not always done well; in particular, Monte Carlo standard errors are often not reported. I present a Stata program, - simsum-, which can output a range of summaries, including bias, precision of one method relative to another,...
Persistent link: https://www.econbiz.de/10005041778
We consider a two-group clinical trial with a survival outcome, in which some subjects may 'cross over' to receive the treatment of the other arm. Our command strbee adjusts for treatment cross-over in one or both arms. This is done by a randomization-respecting method which preserves the...
Persistent link: https://www.econbiz.de/10005053282
In teaching logistic regression for case–control studies, I ask master’s students in epidemiology to assess an interaction between a 2-level exposure and a 4-level exposure using a likelihood-ratio test. Theory suggests that the test statistic has 3 degrees of freedom, but Stata uses 2...
Persistent link: https://www.econbiz.de/10005053304
Network meta-analysis involves synthesising the scientific literature comparing several treatments. Typically, two-arm and three-arm randomized trials are synthesized, and the aim is to compare treatments that have not been directly compared and often to rank the treatments. A difficulty is that...
Persistent link: https://www.econbiz.de/10010897934
A comprehensive range of user-written commands for meta-analysis is available in Stata and documented in detail in the recent book Meta-Analysis in Stata (Sterne, ed., 2009, [Stata Press]).The purpose of this session is to describe these commands, with a focus on recent developments and areas in...
Persistent link: https://www.econbiz.de/10008642117