The car sequencing problem determines sequences of different car models launched down a mixed-model assembly line. To avoid work overloads of workforce, car sequencing restricts the maximum occurrence of labor-intensive options, e.g., a sunroof, by applying sequencing rules. We consider this...

The car sequencing problem determines sequences of different car models launched down a mixed-model assembly line. To avoid work overloads of workforce, car sequencing restricts the maximum occurrence of labor-intensive options, e.g., a sunroof, by applying sequencing rules. We consider this...

Background: Digital supply chain twins (DSCT) are gaining increased attention in academia and practice and their positive impact on logistics and supply chain management (LSCM) performance is often highlighted. Still, LSCM executives are hesitant regarding DSCT implementation. One reason is the...

In practice, most projects result in cost overruns and schedule slippage due to poor resource management. This paper presents an approach that aims at reducing project duration and costs by empowering project managers to assess different scenarios. The proposed approach addresses combinatorial...

Background: Responding to the increasing demand for Deep Vein Thrombosis (DVT) treatment in the United Kingdom (UK) at times of limited budgets and resources is a great challenge for decision-makers. Therefore, there is a need to fnd innovative policies, which improve operational efciency and...

Healthcare problems are complex; they exhibit both detail and dynamic complexity. It has been argued that Discrete Event Simulation (DES), with its ability to capture detail, is ideal for problems exhibiting this type of complexity. On the other hand, System Dynamics (SD) with its focus on...

The research described in this thesis is aimed to improve our knowledge of barriers to the use of OR (Operations Research) techniques in the manufacturing sector. Numerous issues have been previously identified, but the work has generally been unsystematic, or focused on the OR profession. This...

This paper proposes and investigates the use of embedding sensors in products when designing and manufacturing them to improve the efficiency during their end-of-life (EOL) processing. First, separate design of experiments studies based on orthogonal arrays are carried out for conventional...

Fractures are associated with high economic costs, increased mortality and loss of health related quality of life. Studies have shown that individuals with prior fractures have an increased risk of experiencing subsequent fractures. Therefore secondary fracture prevention appears useful to...