Background:Background: National EQ-5D value sets are developed because preferences for health may vary in different populations. UK values are lower than US values for most of the 243 possible EQ-5D health states. Although similar protocols were used for data collection, analytic choices...

Choosing between preference-based instruments of health-related quality of life (HR-QOL) in particular situations is an important area for research. Even where instruments can be assumed to be measuring the same thing, they may not be interchangeable. The study presented investigates the extent...

The objective of this review was to describe the performance of health-utility measures in valuing the quality-of-life (QOL) impact of changes in osteoarthritis (OA)-related chronic pain when administered within a clinical trial setting. Because the collection of utility data within a clinical...

The factors that may lead to an impaired quality of life in congestive heart failure (CHF) are physical symptoms, psychological problems, treatment adverse effects and social limitation. There are now several general and disease-specific quality-of-life (QOL) questionnaires which have been used...

Objective: Physicians need reliable, valid and sensitive questionnaires to assess QOL related to glaucoma or ocular hypertension. This article presents the psychometric properties of the French version of the National Eye Institute Visual Function Questionnaire - 25 (NEI VFQ-25). Methods: A mail...

Background: In clinical trials, patients have expressed greater satisfaction with inhaled human insulin (EXUBERA(R), Pfizer) than with injectable insulin. No studies to date have attempted to quantify the strength of preferences for these alternative routes of administration. Objective: To...

Background:Background: Patient-reported outcomes (PRO) measures should be valid and accessible to a wide audience. Abstract: Objective:Objective: Cognitive item testing and readability studies were conducted to evaluate how adult headache sufferers (N - 9) understood and responded to the...

In 1997, we published a review in PharmacoEconomics about quality of life (QOL) measurement in patients with schizophrenia. The objective of this article is to provide an update, as well as to revisit the development of the construct of QOL and its measurement as applied to schizophrenia. Since...