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In microarray experiments, several steps may cause sub-optimal quality and the need for quality control is strong. Often the experiments are complex, with several conditions studied simultaneously. A linear model for paired microarray experiments is proposed as a generalisation of the paired...
Persistent link: https://www.econbiz.de/10005246476
Statistical models for spot shapes and signal intensities are used in image analysis of laser scans of microarrays. Most models have essentially been based on the assumption of independent pixel intensity values, but models that allow for spatial correlation among neighbouring pixels can...
Persistent link: https://www.econbiz.de/10005246498
Persistent link: https://www.econbiz.de/10010642401
In microarray experiments quality often varies, for example between samples and between arrays. The need for quality control is therefore strong. A statistical model and a corresponding analysis method is suggested for experiments with pairing, including designs with individuals observed before...
Persistent link: https://www.econbiz.de/10005585078