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reimbursement and pricing of approved drugs, the so-called fourth and fifth hurdles. Methods: We reviewed 38 National Institute for … approved. Thirdly, we considered whether and when each drug was recommended for reimbursement and use by NICE, and whether … conditions of reimbursement applied. Fourthly, for the subset of FDA-approved drugs, we examined formulary placement, cost …
Persistent link: https://www.econbiz.de/10005590240
Specific regulatory guidelines dictate that developing a new drug for osteoporosis will be significantly more expensive and take at least 2 years longer in comparison with other long-term therapies developed using the International Committee on Harmonisation (ICH) general guidelines. Assuming...
Persistent link: https://www.econbiz.de/10005590530
Economic analysis has become increasingly important in healthcare in general, and particularly with respect to pharmaceuticals. Therefore, it is vital that the methods used in such evaluations are carefully scrutinised and refined. However, guidelines contain only a limited number of...
Persistent link: https://www.econbiz.de/10005449056
Optimal management of human immunodeficiency virus type 1 (HIV-1)-infected children requires a commitment from the healthcare delivery system, healthcare providers, and affected families and caregivers. When adequate resources are available (as in most industrialised nations), an aggressive...
Persistent link: https://www.econbiz.de/10005448902
In recent years, the use of alternative therapies has become widespread. In particular, there has been a resurgence in the public's demand for herbal remedies, despite a lack of high-quality evidence to support the use of many of them. Given the increasing pressures to control healthcare...
Persistent link: https://www.econbiz.de/10005405015
Deregulation of antibacterials is a recurrent topic in the debate on pharmaceutical policy. This article focuses on one aspect of pharmaceutical regulation, namely the requirement of a medical prescription for purchasing antibacterials. However, a strategy of deregulation should not only concern...
Persistent link: https://www.econbiz.de/10005449163
licensing bodies and public reimbursement agencies. The present study compares access to licensed and subsidized medicines under …
Persistent link: https://www.econbiz.de/10010579442
Objective: Conflicting recommendations have been made on whom to treat with antibacterials to eradicate Helicobacter pylori . The present analysis aims to explain the basis of such discrepancies. Design and Setting: The decision in favour of or against antibacterial therapy in patients with...
Persistent link: https://www.econbiz.de/10005404790
The objective of this study was to develop, and subsequently test, a Bayesian discrimination model for the purpose of identifying both the personal and the healthcare system characteristics predictive of hospitalisation for the treatment of patients with diabetes mellitus or commonly observed...
Persistent link: https://www.econbiz.de/10005404891
In pharmacoeconomics, the comparison of the costs of 2 different drugs used for the same treatment is of great interest. The problem is especially challenging when the drugs are likely to produce costly adverse effects in a small number of patients, which is often the case. The data are then...
Persistent link: https://www.econbiz.de/10005590319