Stratifying and matching by the propensity score are increasingly popular approaches to deal with confounding in medical studies investigating effects of a treatment or exposure. A more traditional alternative technique is the direct adjustment for confounding in regression models. This paper...

A common approach to analysing clinical trials with multiple outcomes is to control the probability for the trial as a whole of making at least one incorrect positive finding under any configuration of true and false null hypotheses. Popular approaches are to use Bonferroni corrections or...

Continuum and compartmental models are presented as alternative descriptions of the electrical behaviour of a dendrite. The one-dimensional continuum model provides a reference against which the accuracy of compartmental models may be assessed. Traditional compartmental models are shown to be...

Many common option pricing problems require numerical solution techniques. One standard tool is to solve a finite difference approximation to the instrument's fundamental partial differential equation (PDE), with appropriate boundary conditions. The approximation will converge to the true...

Compartmental models of dendrites are the most widely used tool for investigating their electrical behaviour. Traditional models assign a single potential to a compartment. This potential is associated with the membrane potential at the centre of the segment represented by the compartment. All...

In this paper, we describe a new algorithmic approach for parameter estimation in Ratcliff's [(1978). A theory of memory retrieval. Psychological Review, 85 (2), 59-108] diffusion model. This problem, especially if inter-trial variabilities of parameters are included in the model, is...

This paper develops a methodology for approximating the posterior first two moments of the posterior distribution in Bayesian inference. Partially specified probability models that are defined only by specifying means and variances, are constructed based upon second-order conditional...

Likelihood ratio (LR) tests for association and for interaction are examined for three-way contingency tables, particularly the widely used 2 x 2 x K table. Mutual information identities are used to characterize the information decomposition and the logical relationship between the omnibus LR...

The paper investigates the problem of determining patterns of criminal behaviour from official criminal histories, concentrating on the variety and type of offending convictions. The analysis is carried out on the basis of a multivariate latent Markov model which allows for discrete covariates...

In studies of properties of queues, for example in relation to Internet traffic, a subject that is of particular interest is the ‘shape’ of service time distribution. For example, we might wish to know whether the service time density is unimodal, suggesting that service time distribution is...