Congress uses varying degrees of specificity when passing legislation. Sometimes it writes very detailed, exacting laws; other times it leaves these details to implementing agencies. A natural positive question then arises: what factors are critical for understanding the degree of delegation...

Missing data are a frequent problem in cost-effectiveness analysis (CEA) within a randomised controlled trial. Inappropriate methods to handle missing data can lead to misleading results and ultimately can affect the decision of whether an intervention is good value for money. This article...

This study sets out a framework to evaluate the goodness of fit of stochastic mortality models and applies it to six different models estimated using English & Welsh male mortality data over ages 64-89 and years 1961-2007. The methodology exploits the structure of each model to obtain various...

This paper develops a framework for developing forecasts of future mortality rates. We discuss the suitability of six stochastic mortality models for forecasting future mortality and estimating the density of mortality rates at different ages. In particular, the models are assessed individually...

The National Institute for Health and Clinical Excellence (NICE) invited the manufacturer of golimumab (Schering-Plough/Centocor) to submit evidence for the clinical and cost effectiveness of this drug for the treatment of active and progressive psoriatic arthritis (PsA) in patients who have...

type="main" xml:id="rssa12005-abs-0001" <title type="main">Summary</title> <p>The aim of the paper is to compare the accuracy and effectiveness of liquid-based versus conventional cytology when used as part of a process of population screening to reduce the incidence of invasive cervical cancer. Data from split-sample...</p>