Current technologies generate a huge number of single nucleotide polymorphism (SNP) genotype measurements in case-control studies. The resulting multiple testing problem can be ameliorated by considering candidate gene regions. The <Emphasis Type="Bold">minPtest R package provides the first widely accessible...</emphasis>

The bootstrap is a tool that allows for efficient evaluation of prediction performance of statistical techniques without having to set aside data for validation. This is especially important for high-dimensional data, e.g., arising from microarrays, because there the number of observations is...

Modern techniques for fitting generalized additive models mostly rely on basis expansions of covariates using a large number of basis functions and penalized estimation of parameters. For example, a mixed model approach is used to fit a model for children's lung function that allows for...

Purpose One of the currently debated changes in scientific practice is the implementation of data sharing requirements for peer-reviewed publication to increase transparency and intersubjective verifiability of results. However, it seems that data sharing is a not fully adopted behavior among...