This paper develops a real options approach to the optimal sequencing of antiretroviral drug cocktails for HIV/AIDS patients in resource-poor settings. The analysis focuses on the implications of endogenous resistance mutations in the virus that reduce or eliminate the effectiveness of...

There is a general agreement that (a) climate change is one of the most serious environmental problems, that (b) the analysis of climate change is confronted with a large degree of uncertainty and (c) that these uncertainties need to be taken into account to arrive at meaningful policy...