There is a coming wave of novel genetic therapies aiming to treat rare pediatric disease. A large literature investigates the valuation of new treatments, but the valuation of treatments for rare pediatric illness raises a host of unique issues. In this paper, we review the challenges of...

We study the spillover effects of prescription drug monitoring programs (PDMPs) on crime, and in the process inform how policies that restrict access to Rx opioids per se within the healthcare system would impact broader non-health domains. In response to the substantial increase in opioid use...

Despite a vast literature on the determinants of prescription opioid use, the role of health insurance plans has received little attention. We study how the form of Medicare beneficiaries' drug coverage affects the volume of opioids they consume. We find that enrollment in Medicare Advantage,...

There is considerable interest in understanding the broader effects of the opioid crisis on labor supply and social insurance programs in the United States. This paper examines how the recent transition of the opioid crisis from prescription opioids to more prevalent misuse of illicit opioids,...

Without the opioid epidemic, American life expectancy would not have declined prior to 2020. In turn, the epidemic was sparked by the development and marketing of a new generation of prescription opioids and provider behavior is still helping to drive it. There is little relationship between the...

We examine the impact of the drug crisis that has unfolded over the last three decades in the United States on children's living arrangements and environments. Because the current living arrangement could be a result of events that occurred at any point in a child's life, we measure children's...

Recent evidence suggests that the short-term transition of the opioid crisis from prescription opioids to heroin can be attributed to the reformulation of OxyContin, which substantially reduced access to abusable prescription opioids. In this paper, we find that over a longer time horizon,...

The United States has experienced an unprecedented crisis related to the misuse of and addiction to opioids. As of 2018, 128 Americans die each day of an opioid overdose, and total economic costs associated with opioid misuse are estimated to be more than $500 billion annually. The crisis has...

Prescription opioid use among women of reproductive age and pregnant women is relatively common and growing prescription opioid use is associated with a commensurate increase in opioid use disorder (OUD) among pregnant women and neonatal abstinence syndrome (NAS) among infants. In this article,...