The context of community-based interventions presents formidable problems for any evaluation analysis. Group-randomized studies do possess ideal properties in theory, but in practice, grouprandomization might not be a feasible alternative at all or group-randomized studies might be contaminated....

HIV continues to cause the largest number of disability-adjusted life years of any disease in HIV hyperendemic countries (i.e., countries with an adult HIV prevalence 15%). We compare the benefits and costs of two proven biological interventions to reduce the health losses due to the HIV...