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Is the Fda Too Conservative or Too Aggressive? : A Bayesian Decision Analysis of Clinical Trial Design

Montazerhodjat, Vahid - 2015

Implicit in the drug-approval process is a trade-off between Type I and Type II error. We explore the application of Bayesian decision analysis (BDA) to minimize the expected cost of drug approval, where relative costs are calibrated using U.S. Burden of Disease Study 2010 data. The results for...

Persistent link: https://www.econbiz.de/10013016659

Speculative bubbles in present-value models : A Bayesian Markov-switching state space approach

Chan, Joshua; Santi, Caterina - In: Journal of economic dynamics & control 127 (2021), pp. 1-26

Persistent link: https://www.econbiz.de/10012668503

Is the FDA too conservative or too aggressive? : a Bayesian decision analysis of clinical trial design

Isakov, Leah; Lo, Andrew W.; Montazerhodjat, Vahid - In: Journal of econometrics 211 (2019) 1, pp. 117-136

Persistent link: https://www.econbiz.de/10012303603

Large Bayesian VARMAs

Chan, Joshua; Eisenstat, Eric; Koop, Gary - In: Journal of econometrics 192 (2016) 2, pp. 374-390

Persistent link: https://www.econbiz.de/10011704723

Fast and accurate variational inference for large Bayesian VARs with stochastic volatility

Chan, Joshua; Yu, Xuewen - In: Journal of economic dynamics & control 143 (2022), pp. 1-19

Persistent link: https://www.econbiz.de/10013539520

Comparing stochastic volatility specifications for large Bayesian VARs

Chan, Joshua - In: Journal of econometrics 235 (2023) 2, pp. 1419-1446

Persistent link: https://www.econbiz.de/10014471398