Operational protocols are a valuable means for quality control. However, developing operational protocols is a highly complex and costly task. We present an integrated approach involving both intelligent data analysis and knowledge acquisition from experts that supports the development of...

In modern intensive care physiological variables of the critically ill can be reported online by clinical information systems. Intelligent alarm systems are needed for a suitable bedside decision support. The existing alarm systems based on fixed treshholds produce a great number of false...

In critical care extremely high dimensional time series are generated by clinical information systems. This yields new perspectives of data recording and also causes a new challenge for statistical methodology. Recently graphical correlation models have been developed for analysing the partial...

Objectives: To determine how different mathematical time series approaches can be implemented for the detection of qualitative patterns in physiologic monitoring data, and which of these approaches could be suitable as a basis for future bedside time series analysis.

Objectives: Time series analysis techniques facilitate statistical analysis of variables in the course of time. Continuous monitoring of the critically ill in intensive care offers an especially wide range of applications. In an open clinical study time series analysis was applied to the...