Most standard statistical methods treat numerical data as if they were real (infinitenumber- of-decimal-places) observations. The issue of quantization or digital resolution is recognized by engineers and metrologists, but is largely ignored by statisticians and can render standard statistical...

The structural analysis of proteins is fundamental to the analysis of protein functions. In this context, sequence-structure alignment methods are important among the different empirical methods. In order to assess the quality of sequence-structure alignments, a statistical method using a...