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The Diffusion of Science-Driven Drug Discovery : Organizational Change in Pharmaceutical Research

Cockburn, Iain M.; Henderson, Rebecca M.; Stern, Scott - 2021

question in the context of one particularly interesting practice, the adoption of science driven drug discovery by the modern … pharmaceutical industry. Over the past two decades, the established pharmaceutical industry has slowly shifted towards a more science …. The principal finding is that adoption of a science-oriented research approach was a function of initial conditions, or …

Persistent link: https://www.econbiz.de/10013216492

Public-Private Interaction and the Productivity of Pharmaceutical Research

Cockburn, Iain M.; Henderson, Rebecca M. - 2021

We examine the impact of publicly funded biomedical research on the in-house research of the for-profit pharmaceutical industry. Qualitative analysis of the history of the discovery and development of a sample of 21 significant drugs, and a program of interviews with senior managers and...

Persistent link: https://www.econbiz.de/10013223878

Balancing Incentives : the Tension between Basic and Applied Research

Cockburn, Iain M.; Henderson, Rebecca M.; Stern, Scott - 2021

This paper presents empirical evidence that the intensity of research workers' incentives for the distinct tasks of basic and applied research are positively associated with each other. We relate this finding to the prediction of the theoretical literature that when effort is multi-dimensional,...

Persistent link: https://www.econbiz.de/10013232003

Scale, Scope and Spillovers : The Determinants of Research Productivity in the Pharmaceutical Industry

Henderson, Rebecca M.; Cockburn, Iain M. - 2021

This paper presents the results of a study of the determinants of research productivity in the pharmaceutical industry. Using disaggregated, internal firm data at the research program level from ten major pharmaceutical companies, we find no evidence of increasing returns to scale at either the...

Persistent link: https://www.econbiz.de/10013239955

Public & Private Spillovers, Location and the Productivity of Pharmaceutical Research

Furman, Jeffrey L. - 2014

While there is widespread agreement among economists and management scholars that knowledge spillovers exist and have important economic consequences, researchers know substantially less about the quot;micro mechanismsquot; of spillovers -- about the degree to which they are geographically...

Persistent link: https://www.econbiz.de/10012752114