There are a number of approaches to detect candidate gene-disease associations including: (i) 'per-genotype', which looks for any difference across the genotype groups without making any assumptions about the direction of the effect or the genetic model; (ii) 'per-allele', which assumes an...

Non-mixture cure models are derived from a simplified representation of the biological process that takes place after treatment for cancer. These models are intended to represent the time from the end of treatment to the time of first recurrence of the cancer in studies when a proportion of...

Non-mixture cure models (NMCMs) are derived from a simplified representation of the biological process that takes place after treatment for cancer. These models are intended to represent the time from the end of treatment to the time of first recurrence of cancer in studies when a proportion of...