Consider a linear regression model with both quantitative and qualitative factors and an k-dimensional response variable y whose components are equicorrelated for each observation. The D-optimal design problem is investigated when the levels of the qualitative factor interact with the...

We consider a general mixed linear model ℳ without any rank assumptions to the covariance matrix and without any restrictions on the correlation between the random effects vector and the random errors vector. We get the representations of best linear unbiased estimators (BLUEs)/ best linear...