Consider the linear regression model with uncorrelated errors and an experimental design ξ. In the article, we address the problem of calculating the minimal efficiency of ξ with respect to the class [InlineMediaObject not available: see fulltext.] of orthogonally invariant information...

We consider the problem of estimating input parameters for a differential equation model, given experimental observations of the output. As time and cost limit both the number and quality of observations, the design is critical. A generalized notion of leverage is derived and, with this, we...