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Discovering Treatment Effectiveness Via Median Treatment Effects—Applications to Covid-19 Clinical Trials

Mullahy, John - 2021

Comparing median outcomes to gauge treatment effectiveness is widespread practice in clinical and other investigations. While common, such difference-in-median characterizations of effectiveness are but one way to summarize how outcome distributions compare. This paper explores properties of...

Persistent link: https://www.econbiz.de/10013221966

The Effect of Pharmaceutical Utilization and Innovation on Hospitalization and Mortality

Lichtenberg, Frank R. - 2021

This paper presents an econometric analysis of the effect of changes in the quantity and type of pharmaceuticals … hospital stays, bed-days, and surgical procedures declined most rapidly for those diagnoses with the greatest increase in the … an increase of 100 prescriptions is associated with 1.48 fewer hospital admissions, 16.3 fewer hospital days, and 3 …

Persistent link: https://www.econbiz.de/10013232009

Is Drug Coverage a Free Lunch? Cross-Price Elasticities and the Design of Prescription Drug Benefits

Gaynor, Martin - 2007

Recently, many U.S. employers have adopted less generous prescription drug benefits. In addition, the U.S. began to offer prescription drug insurance to approximately 42 million Medicare beneficiaries in 2006. We use data on individual health insurance claims and benefit data from 1997-2003 to...

Persistent link: https://www.econbiz.de/10012778125

Technology Diffusion and Productivity Growth in Health Care

Skinner, Jonathan - 2012

Inefficiency in the U.S. health care system has often been characterized as quot;flat of the curvequot; spending providing little or no incremental value. In this paper, we draw on macroeconomic models of diffusion and productivity to better explain the empirical patterns of outcome improvements...

Persistent link: https://www.econbiz.de/10012754821

Bayesian Adaptive Clinical Trials for Anti‐Infective Therapeutics During Epidemic Outbreaks

Chaudhuri, Shomesh - 2020

In the midst of epidemics such as COVID-19, therapeutic candidates are unlikely to be able to complete the usual multiyear clinical trial and regulatory approval process within the course of an outbreak. We apply a Bayesian adaptive patient-centered model—which minimizes the expected harm of...

Persistent link: https://www.econbiz.de/10012833747

Effects of Prescription Drug Insurance on Hospitalization and Mortality : Evidence from Medicare Part D

Kaestner, Robert - 2014

We examine whether obtaining prescription drug insurance through the Medicare Part D program affected hospital … Medicare Part D was associated with an 8% decrease in the number of hospital admissions, a 7% decrease in Medicare expenditures …

Persistent link: https://www.econbiz.de/10013057818

Human Capital and Organizational Performance : Evidence from the Healthcare Sector

Bartel, Ann - 2011

use detailed longitudinal monthly data on nursing units in the Veterans Administration hospital system to identify how the … human capital (general, hospital-specific and unit or team-specific) of the nursing team on the unit affects patients …

Persistent link: https://www.econbiz.de/10013119951

Returns to Physician Human Capital : Analyzing Patients Randomized to Physician Teams

Doyle, Joseph J. - 2010

Patient sorting can confound estimates of the returns to physician human capital. This paper compares nearly 30,000 patients who were randomly assigned to clinical teams from one of two academic institutions. One institution is among the top medical schools in the country, while the other...

Persistent link: https://www.econbiz.de/10012758577

"Generic Entry and the Pricing of Pharmaceuticals"

Frank, Richard G.; Salkever, David S. - 2022

During the 1980s the share of prescriptions sold by retail pharmacies that was accounted for by generic products roughly doubled. The price response to generic entry of brand-name products has been a source of controversy. In this paper we estimate models of price responses to generic entry in...

Persistent link: https://www.econbiz.de/10014158702

The Effects of Off-Label Drug Use on Disability and Medical Expenditure

Blankart, Katharina; Lichtenberg, Frank R. - 2022

Does using prescription drugs off-label increase disability and medical expenditure? This paper uses a unique dataset to evaluate off-label vs. on-label drug use in the US non-institutionalized population. Patients using drugs off-label have on average $515 higher medical expenditure and...

Persistent link: https://www.econbiz.de/10014077151