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Bayesian Adaptive Clinical Trials for Anti‐Infective Therapeutics During Epidemic Outbreaks

Chaudhuri, Shomesh - 2020

In the midst of epidemics such as COVID-19, therapeutic candidates are unlikely to be able to complete the usual multiyear clinical trial and regulatory approval process within the course of an outbreak. We apply a Bayesian adaptive patient-centered model—which minimizes the expected harm of...

Persistent link: https://www.econbiz.de/10012833747

Is Drug Coverage a Free Lunch? Cross-Price Elasticities and the Design of Prescription Drug Benefits

Gaynor, Martin - 2007

Recently, many U.S. employers have adopted less generous prescription drug benefits. In addition, the U.S. began to offer prescription drug insurance to approximately 42 million Medicare beneficiaries in 2006. We use data on individual health insurance claims and benefit data from 1997-2003 to...

Persistent link: https://www.econbiz.de/10012778125

Effects of Prescription Drug Insurance on Hospitalization and Mortality : Evidence from Medicare Part D

Kaestner, Robert - 2014

We examine whether obtaining prescription drug insurance through the Medicare Part D program affected hospital … Medicare Part D was associated with an 8% decrease in the number of hospital admissions, a 7% decrease in Medicare expenditures …

Persistent link: https://www.econbiz.de/10013057818

Discovering Treatment Effectiveness Via Median Treatment Effects—Applications to Covid-19 Clinical Trials

Mullahy, John - 2021

Comparing median outcomes to gauge treatment effectiveness is widespread practice in clinical and other investigations. While common, such difference-in-median characterizations of effectiveness are but one way to summarize how outcome distributions compare. This paper explores properties of...

Persistent link: https://www.econbiz.de/10013221966

The Effect of Pharmaceutical Utilization and Innovation on Hospitalization and Mortality

Lichtenberg, Frank R. - 2021

This paper presents an econometric analysis of the effect of changes in the quantity and type of pharmaceuticals … hospital stays, bed-days, and surgical procedures declined most rapidly for those diagnoses with the greatest increase in the … an increase of 100 prescriptions is associated with 1.48 fewer hospital admissions, 16.3 fewer hospital days, and 3 …

Persistent link: https://www.econbiz.de/10013232009

Technology Diffusion and Productivity Growth in Health Care

Skinner, Jonathan S. - 2012

Inefficiency in the U.S. health care system has often been characterized as quot;flat of the curvequot; spending providing little or no incremental value. In this paper, we draw on macroeconomic models of diffusion and productivity to better explain the empirical patterns of outcome improvements...

Persistent link: https://www.econbiz.de/10012754821

Human Capital and Organizational Performance : Evidence from the Healthcare Sector

Bartel, Ann P. - 2011

use detailed longitudinal monthly data on nursing units in the Veterans Administration hospital system to identify how the … human capital (general, hospital-specific and unit or team-specific) of the nursing team on the unit affects patients …

Persistent link: https://www.econbiz.de/10013119951

A Primer on the Economics of Prescription Pharmaceutical Pricing in Health Insurance Markets

Berndt, Ernst R. - 2011

The pricing of medical products and services in the U.S. is notoriously complex. In health care, supply prices (those received by the manufacturer) are distinct from demand prices (those paid by the patient) due to health insurance. The insurer, in designing the benefit, decides what prices...

Persistent link: https://www.econbiz.de/10013128277

Does Price Reveal Poor-Quality Drugs? Evidence from 17 Countries

Bate, Roger - 2011

Focusing on 8 drug types on the WHO-approved medicine list, we constructed an original dataset of 899 drug samples from 17 low- and median-income countries and tested them for visual appearance, disintegration, and analyzed their ingredients by chromatography and spectrometry. Fifteen percent of...

Persistent link: https://www.econbiz.de/10013128895

Patient Knowledge and Antibiotic Abuse : Evidence from an Audit Study in China

Currie, Janet - 2010

We ask how patient knowledge of appropriate antibiotic usage affects both physicians prescribing behavior and the physician-patient relationship. We conduct an audit study in which a pair of simulated patients with identical flu-like complaints visits the same physician. Simulated patient A is...

Persistent link: https://www.econbiz.de/10013135233

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