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Investments in Pharmaceuticals Before and After TRIPS
Kyle, Margaret - 2009
We examine the relationship between patent protection for pharmaceuticals and investment in development of new drugs …. Patent protection has increased around the world as a consequence of the TRIPS Agreement, which specifies minimum levels of … intellectual property protection for members of the World Trade Organization. It is generally argued that patents are critical for …
Persistent link: https://www.econbiz.de/10012463181
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Productivity in Pharmaceutical Biotechnology R&D : The Role of Experience and Alliances
Danzon, Patricia Munch - 2003
Using data on over 900 firms for the period 1988-2000, we estimate the effect on phase-specific biotech and pharmaceutical R&D success rates of a firm's overall experience, its experience in the relevant therapeutic category; the diversification of its experience, and alliances with large and...
Persistent link: https://www.econbiz.de/10012469083
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Market Size and Research : Evidence from the Pharmaceutical Industry
Byrski, Dennis; Gäßler, Fabian; Higgins, Matthew J. - National Bureau of Economic Research - 2021
Prior literature has established a link between changes in market size and pharmaceutical innovation; whether a link exists with scientific research remains an open question. If upstream research is not responsive to these changes, the kinds of scientific discoveries that flow into future drug...
Persistent link: https://www.econbiz.de/10012533407
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Pharmaceutical Profits and the Social Value of Innovation
Dranove, David - 2014
Prior research has shown that exogenous shocks to the demand for medical products spur additional product development. These studies do not distinguish between breakthrough products and those that largely duplicate the performance of existing products. In this paper, we use a novel data set to...
Persistent link: https://www.econbiz.de/10012458453
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The Diffusion of Science-Driven Drug Discovery : Organizational Change in Pharmaceutical Research
Cockburn, Iain - 1999
Recent work linking the adoption of key organizational practices to productivity raises an important question: if adoption increases productivity so dramatically, why does adoption across an industry take so long? This paper explores this question in the context of one particularly interesting...
Persistent link: https://www.econbiz.de/10012471425
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Corporate Venture Capital as a Real Option in the Markets for Technology
Ceccagnoli, Marco - 2015
technology acquisition. In our research setting, the most common way to exercise the option post-CVC investment is via technology …
Persistent link: https://www.econbiz.de/10012457244
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Calculating the Costs and Benefits of Advance Preparations for Future Pandemics
Glennerster, Rachel; Snyder, Christopher M.; Tan, … - National Bureau of Economic Research - 2022
six months, generating an expected net present value (NPV) of over $400 billion. A proportionate advance-investment …
Persistent link: https://www.econbiz.de/10013435127
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Evaluation and Learning in R&D Investment
Frankel, Alex; Krieger, Joshua L.; Li, Danielle; … - National Bureau of Economic Research - 2023
We examine the role of spillover learning in shaping the value of exploratory versus incremental R&D. Using data from drug development, we show that novel drug candidates generate more knowledge spillovers than incremental ones. Despite being less likely to reach regulatory approval, they are...
Persistent link: https://www.econbiz.de/10014287391
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Pharmaceutical-embodied technical progress, longevity, and quality of life : drugs as "equipment for your health"
Lichtenberg, Frank R. - 2002
Several econometric studies have concluded that technical progress embodied in equipment is a major source of manufacturing productivity growth. Other research has suggested that, over the long run, growth in the U.S. economy's 'health output' has been at least as large as the growth in...
Persistent link: https://www.econbiz.de/10012469354
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Present at the Revolution : Transformation of Technical Identity for a Large Incumbent Pharmaceutical Firm After the Biotechnological Breakthrough
Zucker, Lynne G. - 1995
This paper is a case study of the transformation in research methods which occurred in a large U.S. pharmaceutical firm as a result of the biotech revolution. This transformation is inconsistent with the hypothesis that technological revolutions make existing firms obsolete and consistent with...
Persistent link: https://www.econbiz.de/10012473634