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Using micro data on virtually all of the drugs and diseases of over 500,000 people enrolled in Puerto Rico's Medicaid … program, we examine the impact of the vintage (original FDA approval year) of drugs used to treat a patient on the patient's 3 … services, and the nature and complexity of illness. We find that people using newer drugs during January-June 2000 were less …
Persistent link: https://www.econbiz.de/10012467803
hypothesis the hypothesis that newer drugs increase the length and quality of life and estimate the rate of progress. To do this … primarily from the 1997 Medical Expenditure Panel Survey. We find that people who used newer drugs had better post …-treatment health than people using older drugs for the same condition, controlling for pre-treatment health, age, sex, race, marital …
Persistent link: https://www.econbiz.de/10012469354
The US Food and Drug Administration (FDA) expends considerable efforts in regulating medications approved for use. Yet the impact of medication labeling changes on brand pharmaceutical products, and whether and what firms do to respond to increased information regarding the safety and efficacy...
Persistent link: https://www.econbiz.de/10012461130
We derive the optimal funding mechanism to incentivize development and production of vaccines against diseases with epidemic potential. In the model, suppliers' costs are private information and investments are noncontractible, precluding cost-reimbursement contracts, requiring fixed-price...
Persistent link: https://www.econbiz.de/10013462668
Different countries have been following different reform paths since the early 1990s. We develop a simple dynamic model of policy reform that captures some of the determinants that underlie these differences. The model emphasizes the interaction between domestic institutions and international...
Persistent link: https://www.econbiz.de/10012457430
of the developing world introduces patent protection for new drug products. This may lead to more research on drugs to … might enhance, or dampen, a firm's responsiveness to the availability of product patents. The picture presented here …
Persistent link: https://www.econbiz.de/10012471281
common rationale for patents. For external effects, this analogy has the important and unrecognized implication that classic …
Persistent link: https://www.econbiz.de/10012469100
producing better products under new patents. Therefore, one may divide up the source of competition facing an innovator into … from production of products on other patents. Previous theoretical and empirical micro -based analyses have emphasized the … competition between-patents through so called therapeutic competition. We estimate that between-patent competition, most of which …
Persistent link: https://www.econbiz.de/10012469403
This paper presents the results of a study of the determinants of research productivity in the pharmaceutical industry. Using disaggregated, internal firm data at the research program level from ten major pharmaceutical companies, we find no evidence of increasing returns to scale at either the...
Persistent link: https://www.econbiz.de/10012474480
Pharmaceutical firms' use of secondary patents to extend periods of exclusivity generates concerns among policymakers … worldwide. In response, some developing countries have introduced measures to curb the grant of these patents. While these … countries with restrictions on secondary patents, India, Brazil, and Argentina. We examine cross-country comparisons of primary …
Persistent link: https://www.econbiz.de/10012455567