How should theory-based entrepreneurs search for strategies to implement their ideas? The theory-based view of strategy posits that decision-makers hold theories about their environment premised on beliefs that should be actively tested. This causal framework, which underlies the theory-based...

Technological advances and genomic sequencing opened the road to personalized medicine: specialized therapies targeted to patients displaying specific molecular alterations. For instance, targeted therapies are now available for 50% of lung cancer patients--with some alterations affecting less...

The U.S. government has funded university research for nearly 80 years, with a significant share of this funding supporting the fixed costs of science through indirect cost recovery (ICR). We explain the history, objectives, and mechanics of ICR policy and review key controversies. We also...

Using newly-collected data on the near-population of U.S. STEM PhD graduates since 1950, we examine who funds PhD training, how many graduates are trained in areas of strategic national importance, and the effects of public investment in PhD training on the scientific workforce. The U.S. federal...

Small businesses have long supplied a disproportionate share of major innovations in the United States. We review a centerpiece policy on this topic: the US Small Business Innovation Research (SBIR) program. We trace its legislative history and summarize program evaluations over the past four...

We develop a method to estimate producers' productivity beliefs in settings where output quantities and input prices are unobservable, and we use it to evaluate allocative efficiency in the market for science. Our model of researchers' labor supply shows that their willingness to pay for their...

Multinational firms play a pivotal role in the global economy, yet economic and finance research has largely examined them in isolation. Economic theory focuses on trade and multinational activity but gives relatively little attention to cross-border mergers, while finance research emphasizes...

Markets for technology provide a vibrant channel through which firms purchase ownership rights to patented inventions. Although such transactions enable firms to secure access to intangible assets originating beyond their borders, they also provide cues to competitors regarding the purchasing...

We examine the performance of startups co-founded by immigrant and native teams. Leveraging unique data linking startups to founders' and employees' employment and education histories, we find native-migrant teams outperform native-only and migrant-only teams. Native-migrant startups have larger...

In the late 1980s, Mexico opened itself to international trade and foreign investment, followed in the early 1990s by China. China and Mexico are still the two countries characterized as middle-income by the World Bank with the highest levels of merchandise exports. Although their measures of...