We analyze the financial performance of a hypothetical portfolio of 120 mRNA vaccine candidates in the preclinical stage targeting 11 emerging infectious diseases. We calibrate the simulation parameters with input from domain experts in mRNA technology and an extensive literature review. We find...

This paper examines the extent to which changes in working-age shares associated with population aging might slow economic growth in upcoming years. We first analyze the economic effects of changing working-age shares in a standard empirical growth model using country panel data from 1950-2015....

We study how pre-pandemic inequalities in America influenced social distancing over the course of the COVID-19 pandemic. Richer counties tended to see more protective mobility responses in the initial (pre-pharmaceutical) phase, but less protective responses later. Near linearity of this income...

Millions of women continue to die during and soon after childbirth, even where the knowledge and resources to avoid this are available. We posit that raising the share of women in parliament can trigger action. Leveraging the timing of gender quota legislation across developing countries, we...

We hypothesize that the impact of antibiotics is moderated by a population's inherent (genetic) resistance to infectious disease. Using the introduction of sulfa drugs in 1937, we show that US states that are more genetically susceptible to infectious disease saw larger declines in their...

This paper uses the severe economic crisis in Turkey in 2008 as a quasi-experiment to evaluate the impact of worsening economic conditions during pregnancy on birth outcomes. Exploiting the temporal and spatial variations in economic hardship across provinces, we show that the deep economic...

This paper uses birth records from California and mothers who move to quantify the absolute and relative importance of birth location in early-life health. Using a model that includes mother and location fixed effects, we find that moving from a below- to an above-median birth weight location...

In order to shed light on the biological and social drivers underlying the dramatic rise in cardiovascular disease risk in lower-income settings, links between these risks and body composition, behavioral and socioeconomic factors in Aceh, Indonesia, are contrasted with the United States. We...