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Comparative Effectiveness Without Head-to-Head Trials: A Method for Matching-Adjusted Indirect Comparisons Applied to Psoriasis Treatment with Adalimumab or Etanercept
Signorovitch, James E.; Wu, Eric Q.; Yu, Andrew P.; … - In: PharmacoEconomics 28 (2010) 10, pp. 935-945
a comparison of adalimumab and etanercept for the treatment of psoriasis. IPD from trials of adalimumab versus placebo … trials. Symptom improvements of ≥75% and ≥90% (as measured by the Psoriasis Area and Severity Index [PASI] score at … psoriasis. …
Persistent link: https://www.econbiz.de/10008519891
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The Cost Effectiveness of Tapered versus Abrupt Discontinuation of Oral Cyclosporin Microemulsion for the Treatment of Psoriasis
Hakkaart-van Roijen, Leona; Verboom, Paul; Redekop, W. Ken - In: PharmacoEconomics 19 (2001) 5, pp. 599-608
cyclosporin in patients with chronic plaque psoriasis. Methods: A cost-effectiveness analysis was performed in parallel with a … plaque psoriasis inadequately controlled with topical treatment. Study perspective: The study was conducted from a societal … cyclosporin in patients with chronic plaque psoriasis. …
Persistent link: https://www.econbiz.de/10005590279
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The Burden of Moderate to Severe Psoriasis: An Overview
Raho, Giovanna; Koleva, Daniela Mihajlova; Garattini, Livio - In: PharmacoEconomics 30 (2012) 11, pp. 1005-1013
Psoriasis is a chronic, immune-mediated skin disorder that affects 1-3% of the general population worldwide. While … considered a non-life-threatening disease, psoriasis represents a social and financial burden for patients and the healthcare …, patients with a diagnosis of psoriasis usually need lifelong care, which also means a lifetime of expenses. We aimed to conduct …
Persistent link: https://www.econbiz.de/10010579446
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Peginterferon alpha-2a (40kD) [Pegasys(R)] Improves HR-QOL Outcomes Compared with Unmodified Interferon alpha-2a [Roferon(R)-A]: In Patients with Chronic Hepatitis C
Rasenack, Jens; Zeuzem, Stefan; Feinman, S. Victor; … - In: PharmacoEconomics 21 (2003) 5, pp. 341-349
interferon alpha-2a. In addition to safety and efficacy, the impact on health-related quality of life may be an important …
Persistent link: https://www.econbiz.de/10005243108
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Burden of Illness in Irritable Bowel Syndrome Comparing Rome I and Rome II Criteria
Badia, Xavier; Mearin, Fermin; Balboa, Agustin; Baro, Eva; … - In: PharmacoEconomics 20 (2002) 11, pp. 749-758
Objectives: To evaluate the burden of illness in irritable bowel syndrome (IBS), in terms of resource utilisation (direct and indirect) and health-related quality of life (HR-QOL), in individuals with IBS who meet Rome I and Rome II criteria. Methods: A cross-sectional study, carried out by...
Persistent link: https://www.econbiz.de/10005243189
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Quality-of-Life Assessment in Patients with Benign Prostatic Hyperplasia: Effects of Various Interventions
Batista-Miranda, Jose-Emilio; Diez, Marta De la Cruz; … - In: PharmacoEconomics 19 (2001) 11, pp. 1079-1090
A literature search was conducted to review quality-of-life (QOL) measurement in patients with benign prostatic hypertrophy (BPH). The different QOL instruments are discussed in relation to their correlation with symptom evaluation in studies of treatment options for BPH. Symptom evaluation of...
Persistent link: https://www.econbiz.de/10005243203
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Quality of Life and Utility in Patients with Non-Small Cell Lung Cancer
Trippoli, Sabrina; Vaiani, Monica; Lucioni, Carlo; … - In: PharmacoEconomics 19 (2001) 8, pp. 855-863
patients with non-small cell lung cancer (NSCLC) using the SF-36 and the EuroQOL questionnaires; 2. to evaluate the impact of … that affected quality of life and utility, the presence of metastasis had the greatest impact: patients with metastasis had …
Persistent link: https://www.econbiz.de/10005243207
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Onychomycosis: Health-Related Quality of Life Considerations
Shaw, James W.; Joish, Vijay N.; Coons, Stephen Joel - In: PharmacoEconomics 20 (2002) 1, pp. 23-36
The symptoms of onychomycosis and their impact on personal appearance are important determinants of patients … developed to assess the impact of onychomycosis and its treatment on health-related quality of life (HR-QOL). The instruments …-Specific Questionnaire, has been incorporated into a clinical trial. Thus, information relating to the impact of onychomycosis treatment on …
Persistent link: https://www.econbiz.de/10004990347
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Health-Related Quality-of-Life Assessments in Patients with Advanced Cancer of the Prostate
Adolfsson, Jan - In: PharmacoEconomics 21 (2003) 4, pp. 241-247
Health-related quality of life (HR-QOL) research, in general, is developing. It is becoming increasingly recognised as being important and knowledge on how to assess HR-QOL is spreading. Modern HR-QOL research should assess prevalence and severity of symptoms or functions, as well as the bother...
Persistent link: https://www.econbiz.de/10005449039
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Treatment of Atopic Dermatitis and Impact on Quality of Life: A Review with Emphasis on Topical Non-Corticosteroids
Schiffner, Roman; Schiffner-Rohe, Julia; Landthaler, Michael - In: PharmacoEconomics 21 (2003) 3, pp. 159-179
review the present literature is analysed concerning impact on quality of life for topically-applicable alternatives to the … increase in impact on quality of life. Since studies used different QOL measurements and vary in inclusion criteria, treatment … active treatment modalities and their impact on quality of life. Consensus meetings are desirable to formulate guidelines for …
Persistent link: https://www.econbiz.de/10005449047