It is well known that information is encoded in the frequency or amplitude of Ca2+ signal and then decoded by target protein. However, few models considered both the encoding and decoding procedures of Ca2+ signal. In this work, a minimal Li–Rinzel model is coupled with a...

The influence of fractal heterogeneity on a spiral wave in an excitable system is numerically studied based on the Barkley model. The heterogeneity is implemented by letting the diffusive coefficient in the heterogeneous area be different from the other area. The results show that fruitful...

The investigation of enzymatic reaction under stochastic effect and spatial effect is an interesting problem. By virtue of Monte Carlo simulation, the stochastic dynamic of enzyme and the related Michaelis–Menten mechanism with stochastic internal noise and spatial diffusion are explored in...

Based on a deterministic cell cycle model, the mesoscopic stochastic differential equations are theoretically derived from the biochemical reactions. The effects of the finite cell size on the cell cycle regulation in the wild type and wee1-cdc25Δ double mutant type are numerically studied by...