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Persistent link: https://www.econbiz.de/10005285142
We propose a spline-based semiparametric maximum likelihood approach to analysing the Cox model with interval-censored data. With this approach, the baseline cumulative hazard function is approximated by a monotone B-spline function. We extend the generalized Rosen algorithm to compute the...
Persistent link: https://www.econbiz.de/10008681733
xml:id="sjos816-abs-0001" type="main" xml:lang="en" <title type="main">ABSTRACT</title>In cancer diagnosis studies, high-throughput gene profiling has been extensively conducted, searching for genes whose expressions may serve as markers. Data generated from such studies have the ‘large d, small n’ feature, with the...
Persistent link: https://www.econbiz.de/10011153111